1994 Jan;15(1):108-13. doi: 10.1093/oxfordjournals.eurheartj.a060361. Isosorbide mononitrate (Monoket) is good for a specific type of chest pain (called angina), but it can cause headaches or dizziness after you take it. The information on this page is written and peer reviewed by qualified clinicians. This does not necessarily mean no interactions exist. Instead, the best way to dispose of your medication is through a medicine take-back program. 46 ratings on Drugs.com. Nitrates, although important for the management of angina pectoris, cause significant headache in many patients. It is not intended as medical advice for individual conditions or treatment. Bethesda, MD 20894, Web Policies [2] It can cause your blood pressure to become dangerously low. Bauer B (expert opinion). These side effects may go away during treatment as your body adjusts to the medicine. If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088). Otherwise, call a poison control center right away. It also relaxes and widens blood vessels in your heart (coronary arteries) which increases the flow of blood to your heart muscle. Does Viagra add to the risks of melanoma? 7.6 out of 10 from a total of Natural Medicines. Is not subject to the Controlled Substances Act. May also be prescribed off label for Esophageal Spasm. Last Revised - 09/15/2019. Continue to take isosorbide even if you feel well. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. The information eHealthMe analyzes includes: Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. This is not a complete list of possible side effects. If you are having difficulty accessing this website, please call or email us at (855) 268-2822 or ada@goodrx.com so that we can provide you with the services you require through alternative means. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information. Can cause dizziness, especially when you change positions, Interacts with erectile dysfunction medications. It is best not to drink alcohol while you are on isosorbide mononitrate. You may report side effects to Health Canada at 1-866-234-2345. Isosorbide mononitrate (Monoket) can cause your blood pressure to drop somewhat. Isosorbide Mononitrate ER Oral: Uses, Side Effects - WebMD Some products have ingredients that could worsen your heart failure. Before taking this medication, tell your doctor or pharmacist if you are allergic to it; or to similar drugs (such as isosorbide dinitrate, nitroglycerin); or if you have any other allergies. Methods: DUMQOL (DUtch Mononitrate Quality of Life) Study Group. Medicines Complete BNF 84th Edition; British Medical Association and Royal Pharmaceutical Society of Great Britain, London. Tell your pharmacist what products you are using, and ask how to use them safely (especially cough-and-cold products, diet aids, or NSAIDs such as ibuprofen/naproxen). Isosorbide mononitrate dilates (widens) blood vessels, making it easier for blood to flow through them and easier for the heart to pump.Isosorbide mononitrate is used to prevent angina attacks ( chest pain ). Natural Medicines. Contact your doctor immediately if you experience any of the following: The following side effects may get better over time as your body gets used to the medication. It is unknown if this medication passes into breast milk. That's why you need to talk with your health care provider before you take herbal supplements if you take prescription medicines. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. This is called a medicine interaction. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Your doctor will prescribe you a short-acting nitrate for you to take if this happens. To avoid this problem, get up slowly, resting your feet on the floor for a few minutes before standing up. Some of the common derivatives include isosorbide dinitrate and isosorbide mononitrate, which are . Accessed Sept. 7, 2022. Duplication for commercial use must be authorized by ASHP. Ask your pharmacist any questions you have about refilling your prescription. Is it safe to drive while on this medicine? This medication performs a vasodilatory function and is therefore used as a treatment for high blood pressure. the unsubscribe link in the e-mail. Isosorbide mononitrate (Monoket) can cause some serious health issues. Patients were randomized to either 60 mg 5-ISMN once daily (od) for two weeks or . Isosorbide Mononitrate (Oral Route) - Mayo Clinic Fish Oil (omega-3 polyunsaturated fatty acids), Email this report to a friend, doctor, or patient, isosorbide mononitrate consumer information. Isosorbide may not work as well after you have taken it for some time or if you have taken many doses. Never take extra doses or stop taking it suddenly unless your provider tells you to do so. information and will only use or disclose that information as set forth in our notice of Elantan, Imdur, Isotard, Monomax, Tardisc, Xismox. People with kidney problems should be able to take the usual dose of isosorbide mononitrate (Monoket). This is called tolerance, and it cannot be fixed by raising the dose of the medication. This content does not have an Arabic version. 55 ratings on Drugs.com. privacy practices. Natural remedies for depression: Are they effective? View World Anti-Doping Agency classifications, Prevention of Thromboembolism in Atrial Fibrillation, Prosthetic Heart Valves - Thrombosis Prophylaxis, Prosthetic Heart Valves - Mechanical Valves - Thrombosis Prophylaxis, Revascularization Procedures - Prophylaxis. Now, youll enjoy a streamlined experience created specifically for healthcare providers. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location one that is up and away and out of their sight and reach. . "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. Isosorbide (C6H10O4), also called D-Isosorbide dinitrate, is a bio-product sourced from starch. Isosorbide mononitrate belongs to the group of medicines called nitrates. https://naturalmedicines.therapeuticresearch.com. Accessed Sept. 7, 2022. Headache, dizziness, lightheadedness, nausea, and flushing may occur as your body adjusts to this medication. Melanoma is one of the most dangerous forms of skin cancer which develops in the skin cells that produce melanin ( the pigment that gives your skin its color). Learn to reduce stress through mindful living. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. What should I know about storage and disposal of this medication? Headache and weakness of left side (both arm and leg) may suggest a brain pathology. Drug information provided by: IBM Micromedex. Unless there is a specific reason you need the brand, the generic medication will be a better value. Receive price alerts, news, and other messages from GoodRx about isosorbide mononitrate (Monoket) and other healthcare topics and relevant savings offers. To provide you with the most relevant and helpful information, and understand which A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. It is usually caused by narrowing of your coronary arteries due to a build-up of a fatty substance called atheroma. ** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. Never take more than the prescribed dose. Herbal supplements and heart medicines may not mix - Mayo Clinic Isosorbide mononitrate belongs to the group of medicines called nitrates. 72% of reviewers reported a positive effect, while 12% reported a negative effect. information highlighted below and resubmit the form. When used regularly on a long-term basis, this helps prevent angina attacks from occurring. The authors assessed the occurrence of angina pectoris and headache by diary cards while taking into account the number of isosorbide dinitrate sublingual puffs and paracetamole tablets required. It also may keep some medicines from working as well as they should, such as: If your health care provider tells you it's OK to use an herbal supplement along with medicine, be careful. This document does not contain all possible drug interactions. View all If you have been told by a doctor you have low levels of iron in your blood (anaemia), or low levels of oxygen in your blood (hypoxaemia). Isosorbide is a medication used to treat and prevent angina pectoris in patients with coronary heart disease. Isosorbide mononitrate (Monoket) can cause headaches, dizziness, or lightheadedness. This medicine is for you. Isosorbide can only be used to prevent angina; it cannot be used to treat an episode of angina once it has begun. May also be prescribed off label for Esophageal Spasm. These relax smooth muscle within the blood vessels, widening them and making it easier for blood and oxygen to reach the heart Calcium antagonists (eg, diltiazem, nifedipine, nimodipine, verapamil). The two dosage regimens were equally efficient for the relief of angina pectoris without development of tolerance. St. John's wort. Accessed Sept. 7, 2022. (2) One in 3 patients never experienced headache from the given dosages. View interaction reports for isosorbide mononitrate and the medicines listed below. URL of this page: https://medlineplus.gov/druginfo/meds/a682348.html. Ginkgo. To help you remember, take it at the same times each day. isosorbide mononitrate (Imdur, Ismo, Monoket) - MedicineNet The list below does not include all possible drug interactions with isosorbide mononitrate (Monoket). Isosorbide Manufacturing: An In-Depth Look at Production Costs and For haemoglobin formation vit. Nitrates (eg, isosorbide dinitrate, isosorbide mononitrate, nitroglycerin). As precautionary measure, it is preferable to avoid the use of isosorbide mononitrate during pregnancy. Cardizem may also be used for purposes not listed in this medication guide. Tachjian A, et al. During pregnancy, this medication should be used only when clearly needed. This should pass after a few days. Background: Nitrates, although important for the management of angina pectoris, cause significant headache in many patients. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. In case of overdose, call the poison control helpline at 1-800-222-1222. To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. Do not keep out-of-date or unwanted medicines. If you notice other effects not listed above, contact your doctor or pharmacist. Consult your doctor before breast-feeding. Do not stop taking isosorbide without talking to your doctor. Isosorbide mononitrate works in two ways. Which drugs or supplements interact with isosorbide mononitrate? If tolerance is suspected during the use of transdermal patches they should be left off for 8-12 hours (usually overnight) in each 24 hours; in the case of modified-release tablets of isosorbide dinitrate (and . It is important that you follow the instructions your doctor gives to you about when to take your doses. Isosorbide immediate-release tablets are used for the management of angina (chest pain) in people who have coronary artery disease (narrowing of the blood vessels that supply blood to the heart). The drug donates nitric oxide to the body, which is similar to all other Isosorbide mononitrates. Aspirin has an average rating of Isosorbide mononitrate dilates (widens) blood vessels, making it easier for blood to flow through them and easier for the heart to pump.Isosorbide mononitrate is used to prevent angina attacks (chest pain). If you become pregnant while taking isosorbide, call your doctor. Isosorbide mononitrate Alternatives Compared - Drugs.com Accessibility Mehta D. Botanical medicines. Botanical medicine A modern perspective. Talk to your doctor about the possible risks of using this medication for your condition. It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. Yet significantly fewer patients had headache on low dosage than on high dosage (45 vs 57, P < 0.02). Accessed Sept. 7, 2022. Isosorbide comes as a tablet, an extended-release (long-acting) tablet, and an extended-release capsule to take by mouth. Older adults may be more sensitive to the side effects of this medication, especially dizziness and lightheadedness, which could increase the risk of falls. Copyright 2023 IBM Watson Health. Your doctor may need to change the doses of your medications or monitor you carefully for side effects. What special precautions should I follow? All rights reserved. Don't drink alcohol while taking isosorbide mononitrate (Monoket). Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. Be sure to talk to your health care provider before you take any herbal supplements if you take prescription medicines. Cao HY, Wu HD, Song ZK, Tang ML, Yang S, Liu Y, Qin L. Pan Afr Med J. Stopping isosorbide mononitrate (Monoket) suddenly can cause you to have a worsening of your chest pain. There are 195 drugs known to interact with https://naturalmedicines.therapeuticresearch.com. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. The most common side-effect is headache. Isosorbide mononitrate tablets and capsules are not suitable to take to treat the pain of an angina attack. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Angina pain develops if part of your heart muscle does not get as much blood and oxygen as it needs. https://naturalmedicines.therapeuticresearch.com. Although unlikely, when this medication is used for a long time, it may not work as well and may require different dosing. Consult your doctor for more details. Accessed Sept. 7, 2022. 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